67-hour, multi-position time-laps of mouse intestinal organoids expressing the cell cycle reporter FUCCI2 (hGem-mVenus and hCdt1-mCherry). Image acquired using Viventis Deep 

Long-term 3D imaging reveals how complex multicellular systems grow and develop and how cells move and interact over time, unlocking critical insights into development, disease, and regeneration. Light sheet microscopy makes this possible by illuminating only a thin section of the sample at a time, dramatically reducing photodamage and preserving sample health. This gentle, high-speed technique delivers crisp, volumetric data over hours or even days, empowering researchers to capture biology as it unfolds, in real time. 

Check out the image gallery to explore the development of multicellular systems such as organoids captured with Viventis light sheet technology.

View Image Gallery 

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Imaging Complex Human-Relevant Models for Early Drug Discovery - Technology Showcase 

25th June 2026

Join Leica Microsystems and leading expertsas they explore how organoids are being used across early drug discovery and translational research workflows, the challenges associated with working with increasingly complex models, and emerging imaging approaches designed to address some of these challenges. 

See the full agenda and register now